RAF265 [927880-90-8]
R0020
Estimated Purity≥98%
Product group Chemicals
Overview
- SupplierLKT Laboratories
- Product NameRAF265 [927880-90-8]
- Delivery Days Customer7
- CertificationResearch Use Only
- Estimated Purity≥98%
- FormatDMSO 100 mg/mL (192.89 mM); Ethanol 33 mg/mL (63.65 mM); Water Insoluble
- Scientific DescriptionB-Raf, VEGFR2, c-Raf, PDGFR, CSF-1R, RET, c-Kit, Src, STE20 inhibitor.
- Storage Instruction-20°C
- UNSPSC12352200
References
- Garcia-Gomez A, Ocio EM, Pandiella A, et al. RAF265, a dual BRAF and VEGFR2 inhibitor, prevents osteoclast formation and resorption. Therapeutic implications. Invest New Drugs. 2013 Feb;31(1):200-5. d PMID: 22773056. Huang T, Karsy M, Zhuge J, et al. B-Raf and the inhibitors: from bench to bedside. J Hematol Oncol. 2013 Apr 25;6:30. PMID: 23617957. Su Y, Vilgelm AE, Kelley MC, et al. RAF265 inhibits the growth of advanced human melanoma tumors. Clin Cancer Res. 2012 Apr 15;18(8):2184-98. Erratum in: Clin Cancer Res. 2012 Aug 15;18(16):4475. PMID: 22351689.