RAF709 [1628838-42-5]
S8690
CAS Number1628838-42-5
Product group Chemicals
Overview
- SupplierSelleck Chemicals
- Product NameRAF709 [1628838-42-5]
- Delivery Days Customer9
- CAS Number1628838-42-5
- CertificationResearch Use Only
- Scientific DescriptionRAF709 is a potent inhibitor of B/C RAF kinase with almost equivalent IC50 values of 0.4 nM for B-RAF and C-RAF, showing a high level of selectivity, demonstrating greater than 99% on-target binding to BRAF, BRAFV600E, and CRAF at 1 muM and very few off-targets with DDR1 (>99%), DDR2 (86%), FRK (92%), and PDGFRb (96%), the only kinases with binding >80% at 1 muM.
- UNSPSC12352200