Ralimetinib [862505-00-8]
HY-13241A
CAS Number862505-00-8
Product group Chemicals
Molecular Weight420.53
Overview
- SupplierMedChem Express
- Product NameRalimetinib [862505-00-8]
- Delivery Days Customer10
- CAS Number862505-00-8
- CertificationResearch Use Only
- Molecular FormulaC24H29FN6
- Molecular Weight420.53
- Scientific DescriptionRalimetinib (LY2228820) is a potent and selective, ATP-competitive inhibitor of p38 MAPK alpha/beta, with IC50s of 5.3 and 3.2 nM, respectively. Ralimetinib (LY2228820) selectively inhibits phosphorylation of MK2 (Thr334), with no effect on phosphorylation of p38alpha MAPK, JNK, ERK1/2, c-Jun, ATF2, or c-Myc[1].
- SMILESNC1=NC2=CC=C(C3=C(C4=CC=C(F)C=C4)N=C(C(C)(C)C)N3)N=C2N1CC(C)(C)C
- UNSPSC12352200