Ralimetinib [862505-00-8]

TargetMol Chemicals

Ralimetinib [862505-00-8]

72

862505-00-8

Chemical

Research Use Only

Ralimetinib

C24H29FN6

420.53

Ralimetinib selectively inhibits phosphorylation of MK2 (Thr334) and has no effect on phosphorylation of p38alpha MAPK, JNK, ERK1/2, c-Jun, ATF2, or c-Myc. Ralimetinib is an effective and selective, ATP-competitive inhibitor of p38 MAPK alpha/beta (IC50s: 5.3 and 3.2 nM, respectively).

3 years

C(C)(C)(C)C=1NC(=C(N1)C2=CC=C(F)C=C2)C=3N=C4N(CC(C)(C)C)C(N)=NC4=CC3

-20°C

12352200