Raltegravir (MK-0518) [518048-05-0]
S2005
CAS Number518048-05-0
Product group Chemicals
Overview
- SupplierSelleck Chemicals
- Product NameRaltegravir (MK-0518) [518048-05-0]
- Delivery Days Customer9
- CAS Number518048-05-0
- CertificationResearch Use Only
- Scientific DescriptionRaltegravir (MK-0518) is a potent integrase (IN) inhibitor for WT and S217Q PFV IN with IC50 of 90 nM and 40 nM in cell-free assays, respectively. It shows greater than 1000-fold selectivity for HIV-1 IN over several related Mg2+-dependent enzyme such as HCV polymerase, HIV reverse transcriptase, HIV RNaseH and human alfa-, bèta-, gamma-polymerases.
- UNSPSC12352200