Ramatroban [116649-85-5]
R0248
Estimated Purity≥98%
Product group Chemicals
Overview
- SupplierLKT Laboratories
- Product NameRamatroban [116649-85-5]
- Delivery Days Customer7
- CertificationResearch Use Only
- Estimated Purity≥98%
- FormatEthanol (30 mg/ml), DMSO (30 mg/ml), DMF (30 mg/ml)
- Scientific DescriptionCRTH2 inhibitor, TxA2 antagonist.; Baynas, BAY u3405
- Storage InstructionAmbient
- UNSPSC12352200
References
- Suzuki Y, Inoue T, Yamamoto A, et al. Prophylactic effects of the histamine H1 receptor antagonist epinastine and the dual thromboxane A2 receptor and chemoattractant receptor-homologous molecule expressed on Th2 cells antagonist ramatroban on allergic rhinitis model in mice. Biol Pharm Bull. 2011;34(4):507-10. PMID: 21467637. Akiyama K, Karaki M, Kobayshi R, et al. IL-16 variability and modulation by antiallergic drugs in a murine experimental allergic rhinitis model. Int Arch Allergy Immunol. 2009;149(4):315-22. PMID: 19295235. Sugimoto H, Shichijo M, Okano M, et al. CRTH2-specific binding characteristics of [3H]ramatroban and its effects on PGD2-, 15-deoxy-Delta12, 14-PGJ2- and indomethacin-induced agonist responses. Eur J Pharmacol. 2005 Nov 7;524(1-3):30-7. PMID: 16256979. Shiraishi Y, Asano K, Nakajima T, et al. Prostaglandin D2-induced eosinophilic airway inflammation is mediated by CRTH2 receptor. J Pharmacol Exp Ther. 2005 Mar;312(3):954-60. PMID: 15528449. Ishizuka T, Matsui T, Okamoto Y, et al. Ramatroban (BAY u 3405): a novel dual antagonist of TXA2 receptor and CRTh2, a newly identified prostaglandin D2 receptor. Cardiovasc Drug Rev. 2004 Summer;22(2):71-90. PMID: 15179446.