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Ramatroban [116649-85-5]

Research Use Only
R0248
LKT Laboratories
Estimated Purity≥98%
Product group Chemicals
€ 198,00
5 mg
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Overview

  • Supplier
    LKT Laboratories
  • Product Name
    Ramatroban [116649-85-5]
  • Delivery Days Customer
    7
  • Certification
    Research Use Only
  • Estimated Purity
    ≥98%
  • Format
    Ethanol (30 mg/ml), DMSO (30 mg/ml), DMF (30 mg/ml)
  • Scientific Description
    CRTH2 inhibitor, TxA2 antagonist.; Baynas, BAY u3405
  • Storage Instruction
    Ambient
  • UNSPSC
    12352200

References

  • Suzuki Y, Inoue T, Yamamoto A, et al. Prophylactic effects of the histamine H1 receptor antagonist epinastine and the dual thromboxane A2 receptor and chemoattractant receptor-homologous molecule expressed on Th2 cells antagonist ramatroban on allergic rhinitis model in mice. Biol Pharm Bull. 2011;34(4):507-10. PMID: 21467637. Akiyama K, Karaki M, Kobayshi R, et al. IL-16 variability and modulation by antiallergic drugs in a murine experimental allergic rhinitis model. Int Arch Allergy Immunol. 2009;149(4):315-22. PMID: 19295235. Sugimoto H, Shichijo M, Okano M, et al. CRTH2-specific binding characteristics of [3H]ramatroban and its effects on PGD2-, 15-deoxy-Delta12, 14-PGJ2- and indomethacin-induced agonist responses. Eur J Pharmacol. 2005 Nov 7;524(1-3):30-7. PMID: 16256979. Shiraishi Y, Asano K, Nakajima T, et al. Prostaglandin D2-induced eosinophilic airway inflammation is mediated by CRTH2 receptor. J Pharmacol Exp Ther. 2005 Mar;312(3):954-60. PMID: 15528449. Ishizuka T, Matsui T, Okamoto Y, et al. Ramatroban (BAY u 3405): a novel dual antagonist of TXA2 receptor and CRTh2, a newly identified prostaglandin D2 receptor. Cardiovasc Drug Rev. 2004 Summer;22(2):71-90. PMID: 15179446.