RANTES antibody [12K10]

GeneTex

RANTES antibody [12K10]

9

WB: 1:500 - 1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

Western Blot, Neutralisation/Blocking

Research Use Only

Monoclonal

12K10

500 ug/ml

Unconjugated

CCL5

C-C motif chemokine ligand 5

beta-chemokine RANTES; C-C motif chemokine 5; chemokine (C-C motif) ligand 5; D17S136E; eoCP; eosinophil chemotactic cytokine; RANTES; regulated upon activation, normally T-expressed, and presumably secreted; SCYA5; SISd; SIS-delta; small inducible cytokine subfamily A (Cys-Cys), member 5; T-cell specific protein p288; TCP228

Mouse

IgG1

C-C motif chemokine 5

This gene is one of several chemokine genes clustered on the q-arm of chromosome 17. Chemokines form a superfamily of secreted proteins involved in immunoregulatory and inflammatory processes. The superfamily is divided into four subfamilies based on the arrangement of the N-terminal cysteine residues of the mature peptide. This chemokine, a member of the CC subfamily, functions as a chemoattractant for blood monocytes, memory T helper cells and eosinophils. It causes the release of histamine from basophils and activates eosinophils. This cytokine is one of the major HIV-suppressive factors produced by CD8+ cells. It functions as one of the natural ligands for the chemokine receptor chemokine (C-C motif) receptor 5 (CCR5), and it suppresses in vitro replication of the R5 strains of HIV-1, which use CCR5 as a coreceptor. Alternative splicing results in multiple transcript variants that encode different isoforms. [provided by RefSeq, Jul 2013]

Human

-20°C or -80°C,2°C to 8°C

12352203