RAP1A Polyclonal Antibody
RD80177A
ApplicationsImmunoHistoChemistry
Product group Antibodies
ReactivityHuman, Mouse, Rat
TargetRAP1A
Overview
- SupplierReddot Biotech
- Product NameRAP1A Polyclonal Antibody
- Delivery Days Customer5
- ApplicationsImmunoHistoChemistry
- CertificationResearch Use Only
- Concentration1 mg/ml
- ConjugateUnconjugated
- Gene ID5906
- Target nameRAP1A
- Target descriptionRAP1A, member of RAS oncogene family
- Target synonymsC21KG; G-22K; GTP-binding protein smg p21A; KREV1; KREV-1; RAP1; Ras-related protein Krev-1; ras-related protein Rap-1A; SMGP21
- HostRabbit
- IsotypeIgG
- Scientific DescriptionThis gene encodes a member of the Ras family of small GTPases. The encoded protein undergoes a change in conformational state and activity, depending on whether it is bound to GTP or GDP. This protein is activated by several types of guanine nucleotide exchange factors (GEFs), and inactivated by two groups of GTPase-activating proteins (GAPs). The activation status of the encoded protein is therefore affected by the balance of intracellular levels of GEFs and GAPs. The encoded protein regulates signaling pathways that affect cell proliferation and adhesion, and may play a role in tumor malignancy. Pseudogenes of this gene have been defined on chromosomes 14 and 17. Alternative splicing results in multiple transcript variants.
- ReactivityHuman, Mouse, Rat
- Storage Instruction-20°C
- UNSPSC12352203