RAPGEF1 Polyclonal Antibody
RD266670A
ApplicationsImmunoFluorescence
Product group Antibodies
ReactivityHuman, Mouse, Rat
TargetRAPGEF1
Overview
- SupplierReddot Biotech
- Product NameRAPGEF1 Polyclonal Antibody
- Delivery Days Customer5
- ApplicationsImmunoFluorescence
- CertificationResearch Use Only
- Concentration1 mg/ml
- ConjugateUnconjugated
- Gene ID2889
- Target nameRAPGEF1
- Target descriptionRap guanine nucleotide exchange factor 1
- Target synonymsC3G; CRK SH3-binding GNRP; GRF2; guanine nucleotide-releasing factor 2 (specific for crk proto-oncogene); Rap guanine nucleotide exchange factor (GEF) 1; rap guanine nucleotide exchange factor 1
- HostRabbit
- IsotypeIgG
- Scientific DescriptionThis gene encodes a human guanine nucleotide exchange factor. It transduces signals from CRK by binding the SH3 domain of CRK, and activating several members of the Ras family of GTPases. This signaling cascade that may be involved in apoptosis, integrin-mediated signal transduction, and cell transformation. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some variants has not been determined.
- ReactivityHuman, Mouse, Rat
- Storage Instruction-20°C
- UNSPSC12352203