RARB antibody, PAb

Biorbyt

RARB antibody, PAb

10

Western Blot

WB: 1:1000 WB

Research Use Only

Polyclonal

Rabbit

IgG

Rabbit polyclonal to RARB. Receptor for retinoic acid. Retinoic acid receptors bind as heterodimers to their target response elements in response to their ligands, all-trans or 9-cis retinoic acid, and regulate gene expression in various biological processes. The RXR/RAR heterodimers bind to the retinoic acid response elements (RARE) composed of tandem 5-AGGTCA-3 sites known as DR1-DR5. In the absence or presence of hormone ligand, acts mainly as an activator of gene expression due to weak binding to corepressors. In concert with RARG, required for skeletal growth, matrix homeostasis and growth plate function.

Human

12352203