RASA4 antibody

GeneTex

RASA4 antibody

9

WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

ImmunoFluorescence, Western Blot, ImmunoCytoChemistry

Research Use Only

Polyclonal

0.9 mg/ml

Unconjugated

RASA4

RAS p21 protein activator 4

Ca2+-promoted Ras inactivator; calcium-promoted Ras inactivator; CAPRI; GAPL; ras GTPase-activating protein 4; rasGAP-activating-like protein 2

Rabbit

IgG

Ras GTPase-activating protein 4

This gene encodes a member of the GAP1 family of GTPase-activating proteins that suppresses the Ras/mitogen-activated protein kinase pathway in response to Ca(2+). Stimuli that increase intracellular Ca(2+) levels result in the translocation of this protein to the plasma membrane, where it activates Ras GTPase activity. Consequently, Ras is converted from the active GTP-bound state to the inactive GDP-bound state and no longer activates downstream pathways that regulate gene expression, cell growth, and differentiation. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]

Human

-20°C or -80°C,2°C to 8°C

12352203