RBBP7 Antibody

Cusabio

RBBP7 Antibody

20

Western Blot, ELISA, ImmunoHistoChemistry

Research Use Only

Polyclonal

Unconjugated

RBBP7

RB binding protein 7, chromatin remodeling factor

RbAp46, SPGFX9, histone-binding protein RBBP7, G1/S transition control protein-binding protein RbAp46, RBBP-7, histone acetyltransferase type B subunit 2, nucleosome-remodeling factor subunit RBAP46, retinoblastoma-binding protein 7, retinoblastoma-binding protein RbAp46, retinoblastoma-binding protein p46

Rabbit

IgG

Histone-binding protein RBBP7

Core histone-binding subunit that may target chromatin remodeling factors, histone acetyltransferases and histone deacetylases to their histone substrates in a manner that is regulated by nucleosomal DNA. Component of several complexes which regulate chromatin metabolism. These include the type B histone acetyltransferase (HAT) complex, which is required for chromatin assembly following DNA replication; the core histone deacetylase (HDAC) complex, which promotes histone deacetylation and consequent transcriptional repression; the nucleosome remodeling and histone deacetylase complex (the NuRD complex), which promotes transcriptional repression by histone deacetylation and nucleosome remodeling; and the PRC2/EED-EZH2 complex, which promotes repression of homeotic genes during development; and the NURF (nucleosome remodeling factor) complex.

Human

-20°C or -80°C

41116161