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RBBP8 antibody

Research Use Only
ORB66941
Biorbyt
ApplicationsWestern Blot
Product group Antibodies
ReactivityHuman, Mouse
TargetRBBP8
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Overview

  • Supplier
    Biorbyt
  • Product Name
    RBBP8 antibody
  • Delivery Days Customer
    16
  • Applications
    Western Blot
  • Applications Supplier
    WB:1:1000-1:5000 WB
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Conjugate
    Unconjugated
  • Gene ID5932
  • Target name
    RBBP8
  • Target description
    RB binding protein 8, endonuclease
  • Target synonyms
    COM1; CTBP-interacting protein; CTIP; DNA endonuclease RBBP8; JWDS; RBBP-8; retinoblastoma binding protein 8; RIM; SAE2; SCKL2; sporulation in the absence of SPO11 protein 2 homolog
  • Host
    Rabbit
  • Protein IDQ99708
  • Protein Name
    DNA endonuclease RBBP8
  • Scientific Description
    Rabbit polyclonal to RBBP8.RBBP8 is a DNA endonuclease that cooperates with the MRN complex in processing meiotic andmitotic double-strand breaks by ensuring both resection and intrachromosomal association of thebroken ends. RBBP8 promotes ATR and RPA recruient to DSBs in S/G2 phase and facilitates thegeneration of ssDNA. RBBP8 may modulate the functions ascribed to BRCA1 in transcriptionalregulation, DNA repair, and/or cell cycle checkpoint control.
  • Reactivity
    Human, Mouse
  • Storage Instruction
    -20°C
  • UNSPSC
    12352203