RBN-3143

MedChem Express

RBN-3143

10

Research Use Only

99.24

C22H28FN3O4S

449.54

RBN-3143 is a potent and NAD+-competitive catalytic PARP14 inhibitor with an IC 50 value of 4 nM. RBN-3143 inhibits PARP14-mediated ADP-ribosylation and stabilizes PARP14 in cell lines. RBN-3143 can be used in research of lung inflammation [1] .

O=C1NC(CSC2CCOCC2)=NC3=CC(OCC4CCN(CC4)C(C)=O)=CC(F)=C13

-20°C,2°C to 8°C

12352200