![RCAS1 / Estrogen Receptor Binding Site Associated, Antigen 9(CPTC-EBAG9-2), CF405S conjugate, 0.1mg/mL [26628-22-8] RCAS1 / Estrogen Receptor Binding Site Associated, Antigen 9(CPTC-EBAG9-2), CF405S conjugate, 0.1mg/mL [26628-22-8]](https://biotium.com/wp-content/uploads/2021/02/view_image-53.jpeg)
RCAS1 / Estrogen Receptor Binding Site Associated, Antigen 9(CPTC-EBAG9-2), CF405S conjugate, 0.1mg/mL [26628-22-8]
BNC042502
ApplicationsWestern Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityBovine, Human, Mouse
TargetEBAG9
Overview
- SupplierBiotium
- Product NameRCAS1 / Estrogen Receptor Binding Site Associated, Antigen 9(CPTC-EBAG9-2), CF405S conjugate, 0.1mg/mL
- Delivery Days Customer9
- ApplicationsWestern Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
- CertificationResearch Use Only
- ClonalityMonoclonal
- Clone IDCPTC-EBAG9-2
- Concentration0.1 mg/ml
- ConjugateOther Conjugate
- Gene ID9166
- Target nameEBAG9
- Target descriptionestrogen receptor binding site associated antigen 9
- Target synonymscancer-associated surface antigen RCAS1; EB9; estrogen receptor-binding fragment-associated gene 9 protein; PDAF; receptor-binding cancer antigen expressed on SiSo cells
- HostMouse
- IsotypeIgG2a
- Protein IDO00559
- Protein NameReceptor-binding cancer antigen expressed on SiSo cells
- Scientific DescriptionEBAG9, also known as RCAS1, is an estrogen-transcribed protein. Soluble and membranous RCAS1 proteins may play a role in the immune escape of tumor cells by promoting T lymphocyte inhibition of growth and apoptosis. RCAS1 is expressed in a wide variety of cancers, including uterine, ovarian, and lung cancer cells, and acts as a ligand for a putative receptor present on peripheral lymphocytes. RCAS1 is highly expressed not only in cancer cells but also in non-tumor bile duct cells subject to immune attack. RCAS1 inhibits the in vitro growth of receptor-expressing cells and induces apoptosis, contributing to the ability of tumor cells to evade host immune surveillance. High expression of RCAS1 significantly correlates with tumor progression and with poor outcome for many cancer patients. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
- SourceAnimal
- ReactivityBovine, Human, Mouse
- Storage Instruction2°C to 8°C
- UNSPSC12352203