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RCAS1 / Estrogen Receptor Binding Site Associated, Antigen 9(CPTC-EBAG9-2), CF405S conjugate, 0.1mg/mL [26628-22-8]

RCAS1 / Estrogen Receptor Binding Site Associated, Antigen 9(CPTC-EBAG9-2), CF405S conjugate, 0.1mg/mL [26628-22-8]

BNC042502
Biotium
ApplicationsWestern Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityBovine, Human, Mouse
TargetEBAG9
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Overview

  • Supplier
    Biotium
  • Product Name
    RCAS1 / Estrogen Receptor Binding Site Associated, Antigen 9(CPTC-EBAG9-2), CF405S conjugate, 0.1mg/mL
  • Delivery Days Customer
    9
  • Applications
    Western Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
  • Certification
    Research Use Only
  • Clonality
    Monoclonal
  • Clone ID
    CPTC-EBAG9-2
  • Concentration
    0.1 mg/ml
  • Conjugate
    Other Conjugate
  • Gene ID9166
  • Target name
    EBAG9
  • Target description
    estrogen receptor binding site associated antigen 9
  • Target synonyms
    cancer-associated surface antigen RCAS1; EB9; estrogen receptor-binding fragment-associated gene 9 protein; PDAF; receptor-binding cancer antigen expressed on SiSo cells
  • Host
    Mouse
  • Isotype
    IgG2a
  • Protein IDO00559
  • Protein Name
    Receptor-binding cancer antigen expressed on SiSo cells
  • Scientific Description
    EBAG9, also known as RCAS1, is an estrogen-transcribed protein. Soluble and membranous RCAS1 proteins may play a role in the immune escape of tumor cells by promoting T lymphocyte inhibition of growth and apoptosis. RCAS1 is expressed in a wide variety of cancers, including uterine, ovarian, and lung cancer cells, and acts as a ligand for a putative receptor present on peripheral lymphocytes. RCAS1 is highly expressed not only in cancer cells but also in non-tumor bile duct cells subject to immune attack. RCAS1 inhibits the in vitro growth of receptor-expressing cells and induces apoptosis, contributing to the ability of tumor cells to evade host immune surveillance. High expression of RCAS1 significantly correlates with tumor progression and with poor outcome for many cancer patients. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
  • Source
    Animal
  • Reactivity
    Bovine, Human, Mouse
  • Storage Instruction
    2°C to 8°C
  • UNSPSC
    12352203