Regorafenib-13C-d3 N-Oxide

TargetMol Chemicals

Regorafenib-13C-d3 N-Oxide

16

Research Use Only

13CC20D3H12ClF4N4O4

502.83

Regorafenib-13C-d3 N-Oxide the 13C and deuterated compound of Regorafenib N-Oxide. Regorafenib N-Oxide has a CAS number of 835621-11-9. Regorafenib N-oxyde M2 is an active metabolite of Regorafenib. Regorafenib is a multi-target inhibitor for VEGFR1/2/3, PDGFRbeta, RET, Kit, and Raf-1 (IC50s: 13/4.2/46, 1.5, 22, 7, and 2.5 nM).

C1(C(N[13C]([2H])([2H])[2H])=O)[N+]([O-])=CC=C(OC2=CC=C(NC(NC3=CC=C(Cl)C(C(F)(F)F)=C3)=O)C(F)=C2)C=1

-20°C

12352200