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ProductsBack/Regorafenib Monohydrate [1019206-88-2]

Regorafenib Monohydrate [1019206-88-2]

Research Use Only
R1626
LKT Laboratories
Estimated Purity≥99%
Product group Chemicals
€ 327,00
100 mg
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Overview

  • Supplier
    LKT Laboratories
  • Product Name
    Regorafenib Monohydrate [1019206-88-2]
  • Delivery Days Customer
    7
  • Certification
    Research Use Only
  • Estimated Purity
    ≥99%
  • Format
    insoluble in water between pH1 and 13, slightly soluble in methanol; ethanol and sparingly soluble in acetone
  • Scientific Description
    VEGFR1/2/3, TIE2, PDGFRbèta, FGFR1, c-Kit, RET, B-Raf inhibitor.; BAY73-4506
  • Storage Instruction
    -20°C
  • UNSPSC
    12352200

References

  • Abou-Elkacem L, Arns S, Brix G, et al. Regorafenib inhibits growth, angiogenesis, and metastasis in a highly aggressive, orthotopic colon cancer model. Mol Cancer Ther. 2013 Jul;12(7):1322-31. PMID: 23619301. Wilhelm SM, Dumas J, Adnane L, et al. Regorafenib (BAY 73-4506): a new oral multikinase inhibitor of angiogenic, stromal and oncogenic receptor tyrosine kinases with potent preclinical antitumor activity. Int J Cancer. 2011 Jul 1;129(1):245-55. PMID: 21170960.