Regorafenib N-oxyde (M2)

MedChem Express

Regorafenib N-oxyde (M2) [835621-11-9]

10

835621-11-9

Research Use Only

99.32

C21H15ClF4N4O4

498.81

Regorafenib N-oxyde M2 is an active metabolite of Regorafenib. Regorafenib is a multi-target inhibitor for VEGFR1/2/3, PDGFRbeta, Kit, RET and Raf-1 with IC 50 s of 13/4.2/46, 22, 7, 1.5 and 2.5 nM, respectively.

FC1=CC(OC2=CC=[N+]([O-])C(C(NC)=O)=C2)=CC=C1NC(NC3=CC(C(F)(F)F)=C(Cl)C=C3)=O

-20°C,2°C to 8°C

12352200