REN Polyclonal Antibody

Reddot Biotech

REN Polyclonal Antibody

5

ELISA, ImmunoHistoChemistry

Research Use Only

Polyclonal

0.3 mg/ml

Unconjugated

REN

renin

ADTKD4; angiotensin-forming enzyme; angiotensinogenase; HNFJ2; renin; renin precursor, renal; RTD

Rabbit

IgG

Renin catalyzes the first step in the activation pathway of angiotensinogen--a cascade that can result in aldosterone release,vasoconstriction, and increase in blood pressure. Renin, an aspartyl protease, cleaves angiotensinogen to form angiotensin I, which is converted to angiotensin II by angiotensin I converting enzyme, an important regulator of blood pressure and electrolyte balance. Transcript variants that encode different protein isoforms and that arise from alternative splicing and the use of alternative promoters have been described, but their full-length nature has not been determined.

Human

-20°C

12352203