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ProductsBack/Reveromycin A [134615-37-5]

Reveromycin A [134615-37-5]

Research Use Only
R1985
LKT Laboratories
Estimated Purity≥98%
Product group Chemicals
€ 423,00
100 ug
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Overview

  • Supplier
    LKT Laboratories
  • Product Name
    Reveromycin A [134615-37-5]
  • Delivery Days Customer
    7
  • Certification
    Research Use Only
  • Estimated Purity
    ≥98%
  • Format
    Soluble in DMF, DMSO, ethanol, ethyl acetate or methanol.
  • Scientific Description
    Isoleucyl-tRNA synthase inhibitor, osteoclast protein synthesis inhibitor.
  • Storage Instruction
    -20°C
  • UNSPSC
    12352200

References

  • Yabumoto T, Miyazawa K, Tabuchi M, et al. Stabilization of tooth movement by administration of reveromycin A to osteoprotegerin-deficient knockout mice. Am J Orthod Dentofacial Orthop. 2013 Sep;144(3):368-80. PMID: 23992809. Hiraoka K, Zenmyo M, Watari K, et al. Inhibition of bone and muscle metastases of lung cancer cells by a decrease in the number of monocytes/macrophages. Cancer Sci. 2008 Aug;99(8):1595-602. PMID: 18754872. Woo JT, Kawatani M, Kato M, et al. Reveromycin A, an agent for osteoporosis, inhibits bone resorption by inducing apoptosis specifically in osteoclasts. Proc Natl Acad Sci U S A. 2006 Mar 21;103(12):4729-34. PMID: 16537392.