Reversine [656820-32-5]
R1885
Estimated Purity≥98%
Product group Chemicals
Overview
- SupplierLKT Laboratories
- Product NameReversine [656820-32-5]
- Delivery Days Customer7
- CertificationResearch Use Only
- Estimated Purity≥98%
- FormatDMSO: 7mg/mL; water: insoluble
- Scientific DescriptionPurine analog; differentiation reversing or inducing agent.
- Storage Instruction4°C
- UNSPSC12352200
References
- Kuo CH, Lu YC, Tseng YS, et al. Reversine induces cell cycle arrest, polyploidy, and apoptosis in human breast cancer cells. Breast Cancer. 2014 May;21(3):358-69. PMID: 22926505. Park JG, Lee DH, Moon YS, et al. Reversine increases the plasticity of lineage-committed preadipocytes to osteogenesis by inhibiting adipogenesis through induction of TGF-bèta pathway in vitro. Biochem Biophys Res Commun. 2014 Mar 28;446(1):30-6. PMID: 24548409. Kim M, Yi SA, Lee H, et al. Reversine induces multipotency of lineage-committed cells through epigenetic silencing of miR-133a. Biochem Biophys Res Commun. 2014 Feb 28;445(1):255-62. PMID: 24513286. Bijian K, Lougheed C, Su J, et al. Targeting focal adhesion turnover in invasive breast cancer cells by the purine derivative reversine. Br J Cancer. 2013 Nov 26;109(11):2810-8. PMID: 24169345. Lu CH, Liu YW, Hua SC, et al. Autophagy induction of reversine on human follicular thyroid cancer cells. Biomed Pharmacother. 2012 Dec;66(8):642-7. PMID: 23089471.