Bio-Connect

Revizinone

HY-100615
MedChem Express
CAS Number133718-29-3
Product group Chemicals
Estimated Purity98.31
Molecular Weight459.55
Sign in to order and to see your custom pricing.
Large volume orders?
Order with a bulk request

Overview

  • Supplier
    MedChem Express
  • Product Name
    Revizinone [133718-29-3]
  • Delivery Days Customer
    10
  • CAS Number
    133718-29-3
  • Estimated Purity
    98.31
  • Molecular Formula
    C26H29N5O3
  • Molecular Weight
    459.55
  • Scientific Description
    Revizinone is a novel selective phosphodiesterase (PDE) inhibitor with IC50 values on this enzyme to 0.036 microM. target: phosphodiesterase (PDE)[3]; IC 50: 0.036 microM; [3] In vivo: The administration of Revizinone improved the haemodynamic profile with an increase in cardiac output, a decrease in systemic vascular resistance and a stable heart rate and mean arterial blood pressure. [1] With regard to reconstitution of contractility and cardiac function Revizinone (E-isomer) was 10 fold more potent than R 79595 and nearly 100 fold more potent than R 80123 (Z-isomer). [2] Revizinone significantly increased global LV function and systolic wall thickening in ischemic areas at doses greater than or equal to 0.16 mg/kg i.v. [4]
  • SMILES
    O=C(N(C1CCCCC1)C)CO/N=C(C2=CC=CC=C2)/C3=CC4=C(N=C(NC(C5)=O)N5C4)C=C3
  • Storage Instruction
    -20°C,2°C to 8°C
  • UNSPSC
    12352200