RGB-286638 free base

Selleck Chemicals

RGB-286638 free base [784210-88-4]

9

Research Use Only

...

RGB-286638 free base is a Cyclin-dependent kinase (CDK) inhibitor that inhibits the kinase activity of cyclin T1-CDK9, cyclin B1-CDK1, cyclin E-CDK2, cyclin D1-CDK4, cyclin E-CDK3, and p35-CDK5 with IC50s of 1, 2, 3, 4, 5 and 5 nM, respectively; also inhibits GSK-3beta, TAK1, Jak2 and MEK1, with IC50s of 3, 5, 50, and 54 nM.

12352200