RGD-4C
R2510
Estimated Purity≥95%
Product group Chemicals
Overview
- SupplierLKT Laboratories
- Product NameRGD-4C
- Delivery Days Customer7
- CertificationResearch Use Only
- Estimated Purity≥95%
- Scientific DescriptionPeptide, used to deliver conjugated drugs to cells; potential alfavbèta3 and alfavbèta5 integrin inhibitor.
- Storage Instruction-20°C
- UNSPSC12352200
References
- Allaume X, El-Andaloussi N, Leuchs B, et al. Retargeting of rat parvovirus H-1PV to cancer cells through genetic engineering of the viral capsid. J Virol. 2012 Apr;86(7):3452-65. PMID: 22258256. Pesonen S, Diaconu I, Cerullo V, et al. Integrin targeted oncolytic adenoviruses Ad5-D24-RGD and Ad5-RGD-D24-GMCSF for treatment of patients with advanced chemotherapy refractory solid tumors. Int J Cancer. 2012 Apr 15;130(8):1937-47. PMID: 21630267. Sarkioja M, Kanerva A, Salo J, et al. Noninvasive imaging for evaluation of the systemic delivery of capsid-modified adenoviruses in an orthotopic model of advanced lung cancer. Cancer. 2006 Oct 1;107(7):1578-88. PMID: 16948124. Van Houdt WJ, Haviv YS, Lu B, et al. The human survivin promoter: a novel transcriptional targeting strategy for treatment of glioma. J Neurosurg. 2006 Apr;104(4):583-92. PMID: 16619663.