RGH-122 [2355304-05-9]

TargetMol Chemicals

RGH-122 [2355304-05-9]

16

Research Use Only

C24H25ClN4O3

452.93

RGH-122 (compound 43), characterized as an orally active, potent, and selective hV1a receptor antagonist, demonstrates significant affinity with a K i value of 0.3 nM and an IC 50 of 0.9 nM. It exhibits microsomal stability, indicated by a CL int value of 13/28/25 microL/min/mg [1].

ClC=1C=C2CC3(CC=4N(C2=CC1)C(=NN4)[C@@H]5CC[C@@H](OC6=CC=CC=N6)CC5)OCCO3

-20°C

12352200