
Western blot All lanes: RGS14 antibody at 3.88ug/ml Lane 1: 293T whole cell lysate Lane 2: Hela whole cell lysate Lane 3: Jurkat whole cell lysate Lane 4: SH-SY5Y whole cell lysate Secondary Goat polyclonal to rabbit IgG at 1/10000 dilution Predicted band size: 62, 22, 45, 37 kDa Observed band size: 62 kDa
RGS14 Antibody
CSB-PA019646ESR1HU
ApplicationsWestern Blot, ELISA
Product group Antibodies
ReactivityHuman
TargetRGS14
Overview
- SupplierCusabio
- Product NameRGS14 Antibody
- Delivery Days Customer20
- ApplicationsWestern Blot, ELISA
- CertificationResearch Use Only
- ClonalityPolyclonal
- ConjugateUnconjugated
- Gene ID10636
- Target nameRGS14
- Target descriptionregulator of G protein signaling 14
- Target synonymsregulator of G-protein signaling 14
- HostRabbit
- IsotypeIgG
- Protein IDO43566
- Protein NameRegulator of G-protein signaling 14
- Scientific DescriptionRegulates G protein-coupled receptor signaling cascades. Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits, thereby driving them into their inactive GDP-bound form. Besides, modulates signal transduction via G protein alpha subunits by functioning as a GDP-dissociation inhibitor (GDI). Has GDI activity on G(i) alpha subunits GNAI1 and GNAI3, but not on GNAI2 and G(o) alpha subunit GNAO1. Has GAP activity on GNAI0, GNAI2 and GNAI3. May act as a scaffold integrating G protein and Ras/Raf MAPkinase signaling pathways. Inhibits platelet-derived growth factor (PDGF)-stimulated ERK1/ERK2 phosphorylation; a process depending on its interaction with HRAS and that is reversed by G(i) alpha subunit GNAI1. Acts as a positive modulator of microtubule polymerisation and spindle organization through a G(i)-alpha-dependent mechanism. Plays a role in cell division. Required for the nerve growth factor (NGF)-mediated neurite outgrowth. Involved in stress resistance. May be involved in visual memory processing capacity and hippocampal-based learning and memory.
- ReactivityHuman
- Storage Instruction-20°C or -80°C
- UNSPSC12352203