Rhesus macaque Flt3 Ligand protein

Biorbyt

Rhesus macaque Flt3 Ligand protein

16

Other Application

HPLC, SDS-PAGE

Research Use Only

Unconjugated

Flt3 ligand (FL) is a recently identified hematopoietic cytokine whose activities are mediated by binding to the transmembrane glycoprotein Flt3. Flt3 was first discovered as a member of the class III subfamily of receptor tyrosine kinases (RTK) whose expression among hematopoietic cells was found to be restricted to highly enriched stem/progenitor cell populations. Additional class III RTKs include the receptors from SCF, M-CSF and PDGF. Not surprisingly, Flt3 ligand is also structurally related to M-CSF and SCF. All three cytokines have been shown to exist both as type I transmembrane proteins and as soluble proteins.

E.coli

-20°C,2°C to 8°C

12352202