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ProductsBack/Rifamycin AF [13292-22-3]
Chemical Structure
Chemical Structure
Chemical Structure

Rifamycin AF [13292-22-3]

Research Use Only
AG-CN2-0321
AdipoGen Life Sciences
CAS Number13292-22-3
DownloadMSDS
Product group Chemicals
Estimated Purity>95%
Molecular Weight725.8
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Overview

  • Supplier
    AdipoGen Life Sciences
  • Product Name
    Rifamycin AF [13292-22-3]
  • Delivery Days Customer
    10
  • CAS Number
    13292-22-3
  • Certification
    Research Use Only
  • Estimated Purity
    >95%
  • Hazard Information
    Warning
  • Molecular Formula
    C38H47NO13
  • Molecular Weight
    725.8
  • Scientific Description
    Ansamycin antibiotic. Intermediate of rifampicin. Selective inhibitor of bacterial DNA-dependent RNA polymerase (RNAP). Effective against mycobacteria and therefore used in research of tuberculosis, leprosy and Mycobacterium avium complex (MAC) infections. - Chemical. CAS: 13292-22-3. Formula: C38H47NO13. MW: 725.8. Semisynthetic. Ansamycin antibiotic. Intermediate of rifampicin. Selective inhibitor of bacterial DNA-dependent RNA polymerase (RNAP). Effective against mycobacteria, and are therefore used in research of tuberculosis, leprosy and mycobacterium avium complex (MAC) infections.
  • SMILES
    OC1=C(NC(/C(C)=C\C=C\[C@H](C)[C@H](O)[C@@H](C)[C@H]([C@@H](C)[C@@H]([C@H](C)[C@H](/C=C/O2)OC)OC(C)=O)O)=O)C(C([H])=O)=C(O)C3=C4C(O[C@@]2(C)C4=O)=C(C)C(O)=C31
  • Storage Instruction
    -20°C,2°C to 8°C
  • UNSPSC
    51280000

References

  • Rifamycins: A General View: S. Riva & L.G. Silvestri; Ann. Rev. Microbiol. 26, 199 (1972)
  • Spin-labeled rifamycin: biological activity: Z.Z. Raykov, et al.; Pharmazie 63, 61 (2008)
  • New anti-tuberculosis agents amongst known drugs: K.A.E. Lougheed, et al.; Tuberculosis 89, 364 (2009)
  • The effect of complexation of 3-formylrifamycin SV macrocyclic ether derivatives with metal cations and small nitrogen-containing organic molecules on antibacterial activity against S. aureus and S. epidermidis: P. Przybylski, et al.; Bioorg. Med. Chem. Lett. 25, 3903 (2015)
  • Rifamycin antibiotics - new compounds and synthetic methods. Part 4: Study of the reaction of 3-formylrifamycin SV with secondary amines and ketones: K. Bujnowski, et al.; Tetrahedr. 71, 158 (2015)