Chemical Structure
Rifamycin AF-DA [16783-97-4]
AG-CN2-0328
Overview
- SupplierAdipoGen Life Sciences
- Product NameRifamycin AF-DA [16783-97-4]
- Delivery Days Customer10
- CAS Number16783-97-4
- CertificationResearch Use Only
- Estimated Purity>90%
- Molecular FormulaC36H45NO12
- Molecular Weight683.7
- Scientific DescriptionAnsamycin antibiotic. Intermediate of rifampicin. Selective inhibitor of bacterial DNA-dependent RNA polymerase (RNAP). Effective against mycobacteria. Therefore used in research of tuberculosis, leprosy and Mycobacterium avium complex (MAC) infections. - Chemical. CAS: 16783-97-4. Formula: C36H45NO12. MW: 683.7. Semisynthetic. Ansamycin antibiotic. Intermediate of rifampicin. Selective inhibitor of bacterial DNA-dependent RNA polymerase (RNAP). Effective against mycobacteria, and are therefore used in research of tuberculosis, leprosy and mycobacterium avium complex (MAC) infections.
- SMILESOC1=C(NC(/C(C)=C\C=C\[C@H](C)[C@H](O)[C@@H](C)[C@H]([C@@H](C)[C@@H]([C@H](C)[C@H](/C=C/O2)OC)O)O)=O)C(C([H])=O)=C(O)C3=C4C(O[C@@]2(C)C4=O)=C(C)C(O)=C31
- Storage Instruction-20°C,2°C to 8°C
- UNSPSC51280000
References
- Rifamycins: A General View: S. Riva & L.G. Silvestri; Ann. Rev. Microbiol. 26, 199 (1972)
- Rifamycin antibiotics: inhibitors of Rauscher murine leukemia virus reverse transcriptase and of purified DNA polymerases from human normal and leukemic lymphoblasts: S.S. Yang, et al.; J. Natl. Cancer Inst. 49, 7 (1972)
- Rifamycin Derivatives Strongly Inhibiting RNA>DNA Polymerase (Reverse Transcriptase) of Murine Sarcoma Viruses: C. Gurgo, et al.; J. Natl. Cancer Inst. 49, 61 (1972)