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ProductsBack/Rifamycin AF-K91725 [13292-38-1]
Chemical Structure
Chemical Structure
Chemical Structure

Rifamycin AF-K91725 [13292-38-1]

Research Use Only
AG-CN2-0327
AdipoGen Life Sciences
CAS Number13292-38-1
DownloadMSDS
Product group Chemicals
Estimated Purity>90%
Molecular Weight829.9
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Overview

  • Supplier
    AdipoGen Life Sciences
  • Product Name
    Rifamycin AF-K91725 [13292-38-1]
  • Delivery Days Customer
    10
  • CAS Number
    13292-38-1
  • Certification
    Research Use Only
  • Estimated Purity
    >90%
  • Molecular Formula
    C45H55N3O12
  • Molecular Weight
    829.9
  • Scientific Description
    Ansamycin antibiotic. Selective inhibitor of bacterial DNA-dependent RNA polymerase (RNAP). Effective against mycobacteria and therefore used in research of tuberculosis, leprosy and Mycobacterium avium complex (MAC) infections. - Chemical. CAS: 13292-38-1. Formula: C45H55N3O12. MW: 829.9. Semisynthetic. Ansamycin antibiotic. Selective inhibitor of bacterial DNA-dependent RNA polymerase (RNAP). Effective against mycobacteria, and are therefore used in research of tuberculosis, leprosy and mycobacterium avium complex (MAC) infections.
  • SMILES
    OC1=C(NC(/C(C)=C\C=C\[C@H](C)[C@H](O)[C@@H](C)[C@H]([C@H]2C)O)=O)C(/C=N/N(C)C3=CC=CC=C3)=C(O)C4=C5C(O[C@@](O/C=C/[C@H](OC)[C@H]([C@H]2OC(C)=O)C)(C)C5=O)=C(C)C(O)=C41
  • Storage Instruction
    -20°C,2°C to 8°C
  • UNSPSC
    51280000

References

  • Rifamycin antibiotics: inhibitors of Rauscher murine leukemia virus reverse transcriptase and of purified DNA polymerases from human normal and leukemic lymphoblasts: S.S. Yang, et al.; J. Natl. Cancer Inst. 49, 7 (1972)
  • Rifamycin Derivatives Strongly Inhibiting RNA>DNA Polymerase (Reverse Transcriptase) of Murine Sarcoma Viruses: C. Gurgo, et al.; J. Natl. Cancer Inst. 49, 61 (1972)
  • Hydrazones of 3-formylrifamycin SV. III. N-(Mono and di)substituted hydrazone derivatives. Synthesis, antibacterial activity, and other biological properties: R. Cricchio, et al.; Farmaco Sci. 30, 704 (1975)
  • QSAR Modeling of Antimycobacterial Activity and Activity Against Other Bacteria of 3-Formyl Rifamycin SV Derivatives: D. Dimov, et al.; Quant. Struct.-Act. Relat. 20, 298 (2001)