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Chemical Structure
Chemical Structure
Chemical Structure

Rifamycin AG [38128-51-7]

Research Use Only
AG-CN2-0329
AdipoGen Life Sciences
CAS Number38128-51-7
Product group Chemicals
Estimated Purity>98%
Molecular Weight751.8
Price on request
Packing Size
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Overview

  • Supplier
    AdipoGen Life Sciences
  • Product Name
    Rifamycin AG [38128-51-7]
  • Delivery Days Customer
    10
  • CAS Number
    38128-51-7
  • Certification
    Research Use Only
  • Estimated Purity
    >98%
  • Hazard Information
    Non-hazardous
  • Molecular Formula
    C38H49N5O11
  • Molecular Weight
    751.8
  • Scientific Description
    Ansamycin antibiotic. Selective inhibitor of bacterial DNA-dependent RNA polymerase (RNAP). Effective against mycobacteria and therefore used in research of tuberculosis, leprosy and Mycobacterium avium complex (MAC) infections. - Chemical. CAS: 38128-51-7. Formula: C38H49N5O11. MW: 751.8. Semisynthetic. Ansamycin antibiotic. Selective inhibitor of bacterial DNA-dependent RNA polymerase (RNAP). Effective against mycobacteria, and are therefore used in research of tuberculosis, leprosy and mycobacterium avium complex (MAC) infections.
  • SMILES
    O=C1C(N2)=C/C(C3=C1C(O)=C(C)C(O[C@]4(C)O/C=C/[C@H](OC)[C@@H](C)[C@@H](OC(C)=O)[C@H](C)[C@H](O)[C@H](C)[C@@H](O)[C@@H](C)/C=C/C=C(C)\C2=O)=C3C4=O)=N\NC(N)=N
  • Storage Instruction
    2°C to 8°C,-20°C
  • UNSPSC
    12352200

References

  • Rifamycin antibiotics: inhibitors of Rauscher murine leukemia virus reverse transcriptase and of purified DNA polymerases from human normal and leukemic lymphoblasts: S.S. Yang, et al.; J. Natl. Cancer Inst. 49, 7 (1972)
  • Rifamycin Derivatives Strongly Inhibiting RNA>DNA Polymerase (Reverse Transcriptase) of Murine Sarcoma Viruses: C. Gurgo, et al.; J. Natl. Cancer Inst. 49, 61 (1972)
  • Interaction of rifamycins with mammalian nucleic acid polymerizing enzymes: V.S. Sethi & P. Okano; Biochim. Biophys. Acta. 454, 230 (1976)