Chemical Structure
Rifamycin AG [38128-51-7]
AG-CN2-0329
Overview
- SupplierAdipoGen Life Sciences
- Product NameRifamycin AG [38128-51-7]
- Delivery Days Customer10
- CAS Number38128-51-7
- CertificationResearch Use Only
- Estimated Purity>98%
- Molecular FormulaC38H49N5O11
- Molecular Weight751.8
- Scientific DescriptionAnsamycin antibiotic. Selective inhibitor of bacterial DNA-dependent RNA polymerase (RNAP). Effective against mycobacteria and therefore used in research of tuberculosis, leprosy and Mycobacterium avium complex (MAC) infections. - Chemical. CAS: 38128-51-7. Formula: C38H49N5O11. MW: 751.8. Semisynthetic. Ansamycin antibiotic. Selective inhibitor of bacterial DNA-dependent RNA polymerase (RNAP). Effective against mycobacteria, and are therefore used in research of tuberculosis, leprosy and mycobacterium avium complex (MAC) infections.
- SMILESO=C1C(N2)=C/C(C3=C1C(O)=C(C)C(O[C@]4(C)O/C=C/[C@H](OC)[C@@H](C)[C@@H](OC(C)=O)[C@H](C)[C@H](O)[C@H](C)[C@@H](O)[C@@H](C)/C=C/C=C(C)\C2=O)=C3C4=O)=N\NC(N)=N
- Storage Instruction-20°C,2°C to 8°C
- UNSPSC51280000
References
- Rifamycin antibiotics: inhibitors of Rauscher murine leukemia virus reverse transcriptase and of purified DNA polymerases from human normal and leukemic lymphoblasts: S.S. Yang, et al.; J. Natl. Cancer Inst. 49, 7 (1972)
- Rifamycin Derivatives Strongly Inhibiting RNA>DNA Polymerase (Reverse Transcriptase) of Murine Sarcoma Viruses: C. Gurgo, et al.; J. Natl. Cancer Inst. 49, 61 (1972)
- Interaction of rifamycins with mammalian nucleic acid polymerizing enzymes: V.S. Sethi & P. Okano; Biochim. Biophys. Acta. 454, 230 (1976)