Chemical Structure
Rifamycin AMI-DA [17096-02-5]
AG-CN2-0330
Overview
- SupplierAdipoGen Life Sciences
- Product NameRifamycin AMI-DA [17096-02-5]
- Delivery Days Customer10
- CAS Number17096-02-5
- CertificationResearch Use Only
- Estimated Purity>90%
- Molecular FormulaC40H53N3O12
- Molecular Weight767.9
- Scientific DescriptionAnsamycin antibiotic. Selective inhibitor of bacterial DNA-dependent RNA polymerase (RNAP). Effective against mycobacteria and therefore used in research of tuberculosis, leprosy and Mycobacterium avium complex (MAC) infections. - Chemical. CAS: 17096-02-5. Formula: C40H53N3O12. MW: 767.9. Semisynthetic. Ansamycin antibiotic. Selective inhibitor of bacterial DNA-dependent RNA polymerase (RNAP). Effective against mycobacteria, and are therefore used in research of tuberculosis, leprosy and mycobacterium avium complex (MAC) infections.
- SMILESOC1=C(NC(/C(C)=C\C=C\[C@H](C)[C@H](O)[C@@H](C)[C@H]([C@@H](C)[C@@H]([C@H](C)[C@H](/C=C/O2)OC)O)O)=O)C(/C=N/N3CCOCC3)=C(O)C4=C5C(O[C@@]2(C)C5=O)=C(C)C(O)=C41
- Storage Instruction-20°C,2°C to 8°C
- UNSPSC51280000
References
- Desacetyl-rifamycins: preparation and antibacterial properties: N. Maggi, et al.; Experientia 24, 209 (1968)
- Rifamycin antibiotics: inhibitors of Rauscher murine leukemia virus reverse transcriptase and of purified DNA polymerases from human normal and leukemic lymphoblasts: S.S. Yang, et al.; J. Natl. Cancer Inst. 49, 7 (1972)
- Rifamycin Derivatives Strongly Inhibiting RNA>DNA Polymerase (Reverse Transcriptase) of Murine Sarcoma Viruses: C. Gurgo, et al.; J. Natl. Cancer Inst. 49, 61 (1972)