Rifamycin O [14487-05-9]

Name: Rifamycin O [14487-05-9]
SKU: AG-CN2-0333_A27
Price: 434 EUR
Availability: BackOrder

AG-CN2-0333

CAS Number14487-05-9

Product group Chemicals

Estimated Purity>90%

Molecular Weight753.8

Overview

Supplier
AdipoGen Life Sciences
Product Name
Rifamycin O [14487-05-9]
Delivery Days Customer
10
CAS Number
14487-05-9
Certification
Research Use Only
Estimated Purity
>90%
Molecular Formula
C39H47NO14
Molecular Weight
753.8
Scientific Description
Ansamycin antibiotic. Selective inhibitor of bacterial DNA-dependent RNA polymerase (RNAP). Effective against mycobacteria and therefore used in research of tuberculosis, leprosy and Mycobacterium avium complex (MAC) infections. - Chemical. CAS: 14487-05-9. Formula: C39H47NO14. MW: 753.8. Semisynthetic. Ansamycin antibiotic. Selective inhibitor of bacterial DNA-dependent RNA polymerase (RNAP). Effective against mycobacteria, and are therefore used in research of tuberculosis, leprosy and mycobacterium avium complex (MAC) infections.
SMILES
O=C1C(NC(/C(C)=C\C=C\[C@H](C)[C@H](O)[C@@H](C)[C@H]([C@@H](C)[C@@H]([C@H](C)[C@H](/C=C/O2)OC)OC(C)=O)O)=O)=CC3(OCC(O3)=O)C4=C5C(O[C@@]2(C)C5=O)=C(C)C(O)=C41
Storage Instruction
-20°C,2°C to 8°C
UNSPSC
51280000

Production of Rifamycin O by Streptomyces 4107 A2: S. Sugawara, et al.; J. Antibiot. 17, 29 (1964)
Rifamycins: A General View: S. Riva & L.G. Silvestri; Ann. Rev. Microbiol. 26, 199 (1972)
The constitution and configuration of rifamycins B, O, S and SV: W. Oppolzer & V. Prelog; Helv. Chim. Acta 56, 2287 (1973)
Comprehensive study on structure-activity relationships of rifamycins: discussion of molecular and crystal structure and spectroscopic and thermochemical properties of rifamycin O: A. Bacchi, et al.; J. Med. Chem. 41, 2319 (1998)
Rifamycins-Mode of Action, Resistance, and Biosynthesis: H.G. Floss & T.-W. Yu; Chem. Rev. 105, 621 (2005)