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ProductsBack/Rifamycin PR-3 [38601-77-3]
Chemical Structure
Chemical Structure
Chemical Structure

Rifamycin PR-3 [38601-77-3]

Research Use Only
AG-CN2-0335
AdipoGen Life Sciences
CAS Number38601-77-3
DownloadMSDS
Product group Chemicals
Estimated Purity>94%
Molecular Weight806.9
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Overview

  • Supplier
    AdipoGen Life Sciences
  • Product Name
    Rifamycin PR-3 [21288-98-2]
  • Delivery Days Customer
    10
  • CAS Number
    38601-77-3
  • Certification
    Research Use Only
  • Estimated Purity
    >94%
  • Molecular Formula
    C43H54N2O13
  • Molecular Weight
    806.9
  • Scientific Description
    Ansamycin antibiotic. Selective inhibitor of bacterial DNA-dependent RNA polymerase (RNAP). Effective against mycobacteria and therefore used in research of tuberculosis, leprosy and Mycobacterium avium complex (MAC) infections. - Chemical. CAS: 21288-98-2. Formula: C43H54N2O13. MW: 806.9. Semisynthetic. Ansamycin antibiotic. Selective inhibitor of bacterial DNA-dependent RNA polymerase (RNAP). Effective against mycobacteria, and are therefore used in research of tuberculosis, leprosy and mycobacterium avium complex (MAC) infections.
  • SMILES
    OC1=C(NC(/C(C)=C\C=C\[C@H](C)[C@H](O)[C@@H](C)[C@H]([C@@H](C)[C@@H]([C@H](C)[C@H](/C=C/O2)OC)OC(C)=O)O)=O)C3=C(N(C)C(C)=C3C(OC)=O)C4=C5C(O[C@@]2(C)C5=O)=C(C)C(O)=C41
  • Storage Instruction
    -20°C,2°C to 8°C
  • UNSPSC
    51280000

References

  • Rifamycin antibiotics: inhibitors of Rauscher murine leukemia virus reverse transcriptase and of purified DNA polymerases from human normal and leukemic lymphoblasts: S.S. Yang, et al.; J. Natl. Cancer Inst. 49, 7 (1972)
  • Rifamycin Derivatives Strongly Inhibiting RNA>DNA Polymerase (Reverse Transcriptase) of Murine Sarcoma Viruses: C. Gurgo, et al.; J. Natl. Cancer Inst. 49, 61 (1972)
  • Reverse transcriptase, RNA tumour virus transformation and derivatives of rifamycin SV: R.C. Ting, et al.; Nat. New Biol. 236, 163 (1972)
  • Interaction between murine type-C virus RNA-directed DNA polymerases and rifamycin derivatives: A.M. Wu & R.C. Gallo; Biochim. Biophys. Acta 340, 419 (1974)