Chemical Structure
Rifamycin S, 8-Methyl- [42898-13-5]
AG-CN2-0337
Overview
- SupplierAdipoGen Life Sciences
- Product NameRifamycin S, 8-Methyl- [42898-13-5]
- Delivery Days Customer10
- CAS Number42898-13-5
- CertificationResearch Use Only
- Estimated Purity>90%
- Molecular FormulaC38H47NO12
- Molecular Weight709.8
- Scientific DescriptionAnsamycin antibiotic. Selective inhibitor of bacterial DNA-dependent RNA polymerase (RNAP). Effective against mycobacteria and therefore used in research of tuberculosis, leprosy and Mycobacterium avium complex (MAC) infections. - Chemical. CAS: 42898-13-5. Formula: C38H47NO12. MW: 709.8. Semisynthetic. Ansamycin antibiotic. Selective inhibitor of bacterial DNA-dependent RNA polymerase (RNAP). Effective against mycobacteria, and are therefore used in research of tuberculosis, leprosy and mycobacterium avium complex (MAC) infections.
- SMILESO=C1C(NC(/C(C)=C\C=C\[C@H](C)[C@H](O)[C@@H](C)[C@H]([C@@H](C)[C@@H]([C@H](C)[C@H](/C=C/O2)OC)OC(C)=O)O)=O)=CC(C3=C4C(O[C@@]2(C)C4=O)=C(C)C(OC)=C31)=O
- Storage Instruction-20°C,2°C to 8°C
- UNSPSC51280000
References
- The constitution and configuration of rifamycins B, O, S and SV: W. Oppolzer & V. Prelog; Helv. Chim. Acta 56, 2287 (1973)
- Letter: Electronegative groups at C-3 of rifamycin S enhance its activity toward DNA-dependent RNA polymerase: M.F. Dampier & H.W. Whitlock; JACS 97, 6254 (1975)