Rift valley fever virus (RVFV) (strain ZH-548 M12) Non-structural protein S (His & Myc)
ORB1976506
Product group Proteins / Signaling Molecules
Overview
- SupplierBiorbyt
- Product NameRift valley fever virus (RVFV) (strain ZH-548 M12) Non-structural protein S (His & Myc)
- Delivery Days Customer10
- Application Supplier NoteReconstitute the lyophilized protein in sterile deionized water. The product concentration should not be less than 100 microg/mL. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing.
- CertificationResearch Use Only
- Estimated Purity98.00%
- Scientific DescriptionPlays a role in the escape of host innate immune response by promoting the degradation of host EIF2AK2/PKR and inhibiting host transcription. Cytoplasmic NSs interacts with host FBXW11 to degrade PKR whereas nuclear pool binds to host FBXO3 to target TFIIH subunit GTF2H1 for proteasomal degradation. Forms filaments in the nucleus that may sequester NSs binding partners, causing cell cycle arrest. Rift valley fever virus (RVFV) (strain ZH-548 M12) Non-structural protein S (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 37.3 kDa and the accession number is P21698.
- SourceRVFV
- Storage Instruction-20°C
- UNSPSC12352202