Rilmenidine (phosphate)

MedChem Express

Rilmenidine (phosphate) [85409-38-7]

10

85409-38-7

98.0

C10H19N2O5P

278.24

Rilmenidine phosphate, an innovative antihypertensive agent, is an orally active, selective I1 imidazoline receptor agonist. Rilmenidine phosphate is an alpha 2-adrenoceptor agonist. Rilmenidine phosphate induces autophagy . Rilmenidine phosphate acts both centrally by reducing sympathetic overactivity and in the kidney by inhibiting the Na + /H + antiport. Rilmenidine phosphate modulates proliferation and stimulates the proapoptotic protein Bax thus inducing the perturbation of the mitochondrial pathway and apoptosis in human leukemic K562 cells [1] [2] [3] .

O=P(O)(O)O.C1(NC(C2CC2)C3CC3)=NCCO1

2°C to 8°C

12352200