(E)-Rilzabrutinib

MedChem Express

Rilzabrutinib [1575596-29-0]

10

1575596-29-0

Research Use Only

99.37

C36H40FN9O3

665.76

Rilzabrutinib (PRN1008) is a reversible covalent, selective and oral active inhibitor of Brutons Tyrosine Kinase (BTK), with an IC50 of 1.3 nM.

NC1=C2C(C3=C(C=C(OC4=CC=CC=C4)C=C3)F)=NN([C@H]5CN(CCC5)C(/C(C#N)=C/C(C)(N6CCN(C7COC7)CC6)C)=O)C2=NC=N1

-20°C,2°C to 8°C

12352200