Rimiducid (AP1903)

Selleck Chemicals

Rimiducid (AP1903) [195514-63-7]

9

Research Use Only

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Rimiducid (AP1903) is a chemical protein dimerizer and binds tightly to the target FKBP fusion protein while binding minimally to the abundant natural FKBP. Rimiducid elicites potent and dose-dependent apoptosis of cells in culture expressing dimerizer-dependent Fas constructs, with an EC50 of ~0.1 nM.

12352200