RIP1 kinase inhibitor 8 [2226735-54-0]

TargetMol Chemicals

RIP1 kinase inhibitor 8 [2226735-54-0]

86

Chemical

Research Use Only

RIP1 kinase inhibitor 8

C18H19F2N5O2

375.37

RIP1 Kinase Inhibitor 8 (Compound 77), a potent and highly selective dihydropyrazole (DHP) RIP1 kinase inhibitor, exhibits an IC50 of 20 nM and effectively prevents necrotic cell death. It also demonstrates a favorable pharmacokinetic profile across multiple species [1].

3 years

C(=O)(N1[C@@H](CC=N1)C2=CC(F)=CC(F)=C2)C3CCN(CC3)C4=NN=C(C)O4

-20°C

51202000