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RIP1 kinase inhibitor 8

Research Use Only
HY-155804
MedChem Express
Molecular Weight375.37
Product group Chemicals
Price on request
Packing Size
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Overview

  • Supplier
    MedChem Express
  • Product Name
    RIP1 kinase inhibitor 8
  • Delivery Days Customer
    14
  • Certification
    Research Use Only
  • Molecular Formula
    C18H19F2N5O2
  • Molecular Weight
    375.37
  • Scientific Description
    RIP1 kinase inhibitor 8 (Compound 77) is a potent and highly selective dihydropyrazole (DHP) RIP1 kinase inhibitor with an IC50 of 20 nM. RIP1 kinase inhibitor 8 prevents necrotic cell death. RIP1 kinase inhibitor 8 shows a favorable pharmacokinetic profile in multiple species[1].
  • SMILES
    O=C(C1CCN(C2=NN=C(O2)C)CC1)N3[C@H](C4=CC(F)=CC(F)=C4)CC=N3
  • UNSPSC
    12352200