Ripasudil (K-115) [887375-67-9]

Biorbyt

Ripasudil (K-115) [887375-67-9]

16

887375-67-9

Research Use Only

C15H23CLFN3O4S

395.8772

K-115, an isoquinolinesulfonamide compound, is a highly selective and potent (IC50 = 31 nM) Rho-kinase inhibitor; is in Phase II clinical development in patients with POAG or ocular hypertension.

Cl[H].S(C1=C([H])C([H])=C([H])C2=C([H])N=C([H])C(=C12)F)(N1C([H])([H])C([H])([H])C([H])([H])N([H])C([H])([H])[C@]1([H])C([H])([H])[H])(=O)=O.O([H])[H].O([H])[H]

12352200