RK-701 [2648855-18-7]

MedChem Express

RK-701 [2648855-18-7]

10

2648855-18-7

Research Use Only

98.04

C26H30N4O3

446.54

RK-701 is an highly selective and non-genotoxic inhibitor of G9a with IC50 value of 23-27 nM. RK-701 selectively up-regulates HbF, gamma- Globin, BGLT3 expression, down-regulates H3K9me2 expression. RK-701 also has inhibition for BCL11A and ZBTB7A[1].

CC1=C(C(N[C@@H](CCC2CC2)C(NC3=CC=C(C=C3)C#N)=O)=O)NC(CC(C)(C4)C)=C1C4=O

-20°C,2°C to 8°C

12352200