RKI-1447 (dihydrochloride)

MedChem Express

RKI-1447 (dihydrochloride) [1782109-09-4]

10

1782109-09-4

Research Use Only

98.04

C16H16Cl2N4O2S

399.29

RKI 1447 dihydrochloride is a potent and selective ROCK inhibitor with IC 50 s of 14.5 and 6.2 nM for ROCK1 and ROCK2 , respectively [1] . RKI 1447 dihydrochloride suppresses colorectal carcinoma cell growth and promotes apoptosis [2] .

O=C(NC1=NC(C2=CC=NC=C2)=CS1)NCC3=CC=CC(O)=C3.[H]Cl.[H]Cl

2°C to 8°C

12352200