RMC-4550 [2172651-73-7]
ORB573188
CAS Number2172651-73-7
Product group Chemicals
Molecular Weight437.365
Overview
- SupplierBiorbyt
- Product NameRMC-4550 [2172651-73-7]
- Delivery Days Customer16
- CAS Number2172651-73-7
- CertificationResearch Use Only
- Molecular FormulaC21H26Cl2N4O2
- Molecular Weight437.365
- Scientific DescriptionRMC-4550 (RMC4550) is a potent, selective, allosteric inhibitor of SHP2 with IC50 of 0.58 nM (full-length SHP2 enzyme), suppresses pERK signaling in Calu-1 cells with IC50 of 7 nM.
- SMILESClC1=C(Cl)C(C2=NC(CO)=C(N3CCC4(CO[C@@H](C)[C@H]4N)CC3)N=C2C)=CC=C1
- UNSPSC12352200