RNase R

Applied Biological Materials

RNase R

9

PCR and Proteins

Research Use Only

Save when you buy abms RNase R bundled with RNaseOFF Ribonuclease Inhibitor (Cat. No. G138). RNase R is an E. coli exoribonuclease which exhibits 3-to-5 exonuclease activity, efficiently digesting nearly all linear RNA species. This enzyme does not digest circular, lariat, or double stranded RNA with short 3 overhangs (less than seven nucleotides). As such, this enzyme is ideally suited to the study of lariat RNA produced by traditional splicing, as well as circRNAs which arise through back-splicing. By removing linear RNAs from cellular or RNA extracts, RNase R greatly facilitates the identification of circular species through RNA-sequencing. This enables researchers to probe the landscape of splicing events with greater depth.

-20°C

12352204