RO4929097 --- gamma-Secretase Inhibitor
BS-60007C
Estimated Purity98.0
Product group Chemicals
Overview
- SupplierBioss
- Product NameRO4929097 --- gamma-Secretase Inhibitor [847925-91-1]
- Delivery Days Customer16
- CertificationResearch Use Only
- Estimated Purity98.0
- Scientific DescriptionRO4929097 is a highly potent and selective gamma-secretase inhibitor with an IC50 ~4 nM. It can cause a dramatic reduction of the intracellular Notch level and lead to significantly decreased expression of the Notch transcriptional target genes, such as Hes1. It exhibits potent inhibitory activity of Notch signaling in tumor cells. Currently RO4929097 is in multiple phase I/II clinical trials to treat cancer.
- Storage Instruction-20°C
- UNSPSC51202000