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ProductsBack/RO495 [1258296-60-4]
Chemical Structure
Chemical Structure
Chemical Structure

RO495 [1258296-60-4]

Research Use Only
SYN-1128
SYNkinase
CAS Number1258296-60-4
DownloadDatasheet
Product group Chemicals
Estimated Purity>95%
Molecular Weight389.2
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Overview

  • Supplier
    SYNkinase
  • Product Name
    RO495 [1258296-60-4]
  • Delivery Days Customer
    10
  • CAS Number
    1258296-60-4
  • Certification
    Research Use Only
  • Estimated Purity
    >95%
  • Molecular Formula
    C17H14Cl2N6O
  • Molecular Weight
    389.2
  • Scientific Description
    Chemical. CAS: 1258296-60-4. Formula: C17H14Cl2N6O. MW: 389.2. RO495 is a very potent TYK2 inhibitor with a IC(50) of 1.5nM on TYK2 as tested in cell-based pharmacological assays including the compound-mediated effects on STAT5 phosphorylation in Set-2 lysates or IL-12 stimulation of NK92 using the Meso Scale Discovery (MSD) technology. - RO495 is a very potent TYK2 inhibitor with a IC(50) of 1.5nM on TYK2 as tested in cell-based pharmacological assays including the compound-mediated effects on STAT5 phosphorylation in Set-2 lysates or IL-12 stimulation of NK92 using the Meso Scale Discovery (MSD) technology.
  • Storage Instruction
    2°C to 8°C,-20°C
  • UNSPSC
    12352200