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ProductsBack/Robotnikinin [1132653-79-2]
Chemical Structure
Chemical Structure
Chemical Structure

Robotnikinin [1132653-79-2]

Research Use Only
AG-CR1-0069
AdipoGen Life Sciences
CAS Number1132653-79-2
DownloadMSDS
Product group Chemicals
Estimated Purity>97%
Molecular Weight454.9
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Overview

  • Supplier
    AdipoGen Life Sciences
  • Product Name
    Robotnikinin [1132653-79-2]
  • Delivery Days Customer
    10
  • CAS Number
    1132653-79-2
  • Certification
    Research Use Only
  • Estimated Purity
    >97%
  • Molecular Formula
    C25H27ClN2O4
  • Molecular Weight
    454.9
  • Scientific Description
    Chemical. CAS: 1132653-79-2. Formula: C25H27ClN2O4. MW: 454.9. Synthetic. Sonic hedgehog (Shh) signaling modulator. Inhibits the Shh pathway in human cell lines upstream of Smo. Targets the Shh N-terminal protein. - Sonic hedgehog (Shh) signaling modulator [1, 2, 3]. Inhibits the Shh pathway in human cell lines upstream of Smo [1, 2, 3]. Targets the Shh N-terminal protein [1, 2, 3].
  • SMILES
    ClC1=CC=C(CNC(=O)C[C@@H]2C\C=C\CCC(=O)O[C@@H](CNC2=O)C2=CC=CC=C2)C=C1
  • Storage Instruction
    -20°C,2°C to 8°C
  • UNSPSC
    12352200

References

  • A small molecule that binds Hedgehog and blocks its signaling in human cells: B.Z. Stanton, et al.; Nat. Chem. Biol. 5, 154 (2009)
  • Syntheses of aminoalcohol-derived macrocycles leading to a small-molecule binder to and inhibitor of Sonic Hedgehog: L.F. Peng, et al.; Bioorg. Med. Chem. Lett. 19, 6319 (2009)
  • Small-molecule modulators of the Sonic Hedgehog signaling pathway: B.Z. Stanton & L.F. Peng; Mol. Biosyst. 6, 44 (2010) (Review)